This Healthy Turkey Tetrazzini is a lightened-up version of the classic dish. It’s made with turkey, zoodles, and a creamy Parmesan cheese sauce. This dish is perfect for a weeknight meal or to serve to guests.
If you are a fan of Instant Pot Chicken Tetrazzini then this is the recipe for you. It’s creamy and comforting, yet helps you achieve your health goals!

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Low Carb Tetrazzini
One of the best things about this easy recipe is that it is full of zucchini noodles. I love to use zucchini because it’s filled with health benefits, such as being a great source of antioxidants, vitamins, and minerals.
Why I Love This Recipe
The classic dish, but with a healthier twist. This Healthy Tetrazzini is made from lean turkey and zoodles in creamy Parmesan cheese sauce! It’s perfect for busy weeknights when you need something easy!
- Easy to make
- Perfect for picky eaters
- Fills the house with a delicious aroma
If you love creamy low carb recipes like this, then next time you may want to give this Low Carb Chicken Broccoli Casserole a try.
Ingredients

You only need a few simple ingredients to make this simple recipe. All of these ingredients are easy to find at your local grocery store. You can find the full list of ingredients in the recipe card below.
- zucchini noodles – I used frozen zucchini noodles that are thawed and drained.
- mushrooms – I used fresh sliced baby bella mushrooms.
- cooked turkey – This is a great way to use up leftover turkey from Thanksgiving.
Substitutions
Turkey – If you don’t have leftover turkey on hand, you can use cooked ground turkey, even chopped turkey tenderloin instead.
Mushrooms: If you don’t have baby bella mushrooms, you can use white or button mushrooms instead.
Variations / Options / Add-Ins
Here are a few ways that you personalize this simple weeknight meal.
Add vegetables: You can add other vegetables to this dish, such as frozen peas or spinach.
Chicken: Instead of turkey, you can use cut-up chicken.
Spicy: Add a little cayenne pepper to the sauce to give it a little bit of a kick.
Equipment Needed / Helpful Tools
You only need a few kitchen tools to help you make this low-carb recipe.
- 9×13 casserole dish – I recommend using a glass or ceramic dish.
- large skillet – You can use any type of nonstick skillet that you have on hand.
How to Make Healthy Turkey Tetrazzini
This recipe comes together in just a few simple steps. Follow these instructions and you will have a creamy family-friendly recipe in no time at all.
Step 1: Preheat the oven and grease a baking dish
Preheat the oven to 400 degrees. Prepare a 9 x 13 casserole dish with nonstick cooking spray.
Step 2: Saute the onion, mushrooms, and garlic in a skillet
In a large skillet over medium heat, melt the butter. Add the onion, mushrooms, salt, pepper, and garlic to the saucepan. Cook until the onions are softened, stirring often. Then, add the turkey to the skillet and heat through.

Step 3: Add the heavy cream to the skillet
Add the heavy cream to the skillet, stirring to combine. Bring the sauce to a boil. Reduce the heat and simmer for an additional two minutes before stirring in ¾ cup of the cheese. Remove from heat.

Step 4: Add the zucchini noodles, and sauce to a casserole dish and bake
Toss the sauce together with the zucchini noodles and place in the prepared casserole dish. Top with the remaining cheese and bake for 40 minutes.

Serving Suggestions
This turkey tetrazzini recipe is great by itself, however, if you want to add a flavorful and crispy side dish you can make these Air Fryer Keto Brussels Sprouts. End this meal with a sweet treat like these Keto Chocolate Chip Pecan Cookies.

Pro Tips
Here are a few tips to make sure that this turkey tetrazzini turns out perfectly every time that you make it.
- Use frozen zucchini noodles for this recipe. Thaw the noodles and drain before adding them to the recipe. If you use fresh zucchini, you will need to cook it first before adding it to the recipe.
- I used leftover turkey in this recipe, but you can also use ground turkey. Make sure that you cook it first.
- I like to garnish this with fresh parsley for a pop of color.
- If you are not low-carb you could also make this recipe with cooked pasta, like egg noodles, linguine or spaghetti noodles.
FAQs
Do you have questions about this recipe? Here are the answers to the most commonly asked question for this recipe.
I recommend storing leftovers of this recipe in an airtight container in the fridge for 3 days.
When you are ready to eat, heat the tetrazzini in the microwave for 2-3 minutes or until heated through. You can also reheat this dish in the oven at 350 degrees for 10-15 minutes. If this dish is too dry, you want to add a little cream or chicken broth to the sauce.
No, but it is much easier to use them in this recipe. If you decide to use fresh zucchini, you will need to cook them first before adding them to the recipe.
More Turkey Recipes
If you like turkey, give these recipes a try:
Ready to get cooking? Print off the recipe card below or toggle on Cook Mode to keep your screen from going dark while you follow along on your phone or tablet.
📋 Recipe

Healthy Turkey Tetrazzini
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Equipment
- Large skillet
- 9×13 casserole dish
Ingredients
- 23 ounces zucchini noodles thawed and well drained
- 2 tablespoons butter
- ½ onion diced
- 8 ounces baby bella mushrooms sliced
- ½ teaspoon salt
- ½ teaspoon pepper
- 1 clove garlic minced
- 3 cups cooked turkey cut into bite-size pieces
- 1 ½ cups heavy cream
- 1 cup shredded mozzarella cheese divided
Instructions
- Preheat the oven to 400 degrees. Prepare a 9 x 13 casserole dish with nonstick cooking spray.
- In a large skillet over medium heat, melt the butter. Add the onion, mushrooms, salt, pepper, and garlic to the saucepan. Cook until the onions are softened, stirring often. Then, add the turkey to the skillet and heat through.
- Add the heavy cream to the saucepan, stirring to combine. Bring the sauce to a boil. Reduce the heat and simmer for an additional two minutes before stirring in ¾ cup of the cheese. Remove from heat.
- Toss the sauce together with the zucchini noodles and place in the prepared casserole dish. Top with the remaining cheese and bake for 40 minutes.
Notes
- Use frozen zucchini noodles for this recipe. Thaw the noodles and drain before adding them to the recipe. If you use fresh zucchini, you will need to cook it first before adding it to the recipe.
- I used leftover turkey in this recipe, but you can also use ground turkey. Make sure that you cook it first.
- I like to garnish this with fresh parsley for a pop of color.
What do you suggest as a substitute for mushrooms?
Also, if using pasta, how much?
Thanks!!
Instead of mushrooms, you can use diced zucchini, bell pepper, cauliflower, diced eggplant, spinach or kale, chopped artichoke hearts or diced celery.
Instead of the zucchini noodles, you can substitute with about 8 ounces of dry pasta (roughly 4 cups cooked).